The Healthy Pitmaster

Science

Research Studies & Study Summaries

The Effects of Neigene on skin health and function in females

After four weeks of daily Neigene use, every measured skin outcome showed statistically significant improvement. Dermal density increased 6.47%, skin thickness increased 1.47%, melanin decreased 3.13%, the number of dark spots decreased 37.34%, and the area of dark spots decreased 34.5%. The results showed improvements in both skin structure and visible signs of hyperpigmentation.

Human Study

The Clinical Benefits of a 30-day Comprehensive Health and Fitness Program

After 30 days of structured group coaching and Unicity supplementation, participants experienced significant reductions in neck, waist and hip circumference, total cholesterol, LDL cholesterol, triglycerides, blood glucose, and HbA1c. The findings showed meaningful improvements across multiple markers of cardiometabolic health in as little as one month.

Human Study

A Test of the Clinical Benefits of a 60-Day Comprehensive Health and Fitness Program

After 60 days of structured group coaching and Unicity supplementation, participants experienced significant reductions in neck, waist and hip circumference, total cholesterol, LDL cholesterol, triglycerides, and blood glucose. The results showed broad improvements across multiple markers of cardiometabolic health.

Human Study

A Test of the Clinical Relevance of a 90-day Health Transformation Program

After 90 days of structured coaching, meal planning, and Unicity supplementation, participants experienced significant reductions in neck, waist and hip circumference, total cholesterol, LDL cholesterol, triglycerides, blood glucose, and HbA1c. The results showed broad improvements across multiple markers of cardiometabolic health.

Human Study

The Effects of a Proprietary Fiber Supplement on Blood Markers and Gut Bacteria

After 12 weeks of twice-daily fiber supplementation, every cardiometabolic blood marker measured was lower: blood glucose decreased 11%, HbA1c 9%, total cholesterol 10%, LDL cholesterol 9%, VLDL cholesterol 6%, TG:HDL ratio 4%, and triglycerides 2%. Microbial diversity also increased by 58%, with substantial increases in several beneficial gut bacteria, including a 38-fold increase in Lactobacillus and a 12-fold increase in Bifidobacterium.

Human Study

Fiber Supplementation with Unicity Balance Significantly Lowers the Postprandial Glucose Response to a High-Carbohydrate Meal in Healthy Adults

Taking Unicity Balance 15 minutes before a high-carbohydrate breakfast significantly reduced the post-meal glucose response. Glucose levels were 34% lower at 30 minutes and 37% lower at 45 minutes compared with the control condition, while the overall two-hour glucose response was 43% lower. The maximum rise in glucose was also reduced from 78 mg/dL to 52 mg/dL.

Human Study Clinical Trial Randomized

A Novel Yerba Mate Supplement Improves Objective Outcomes Indicative of Happiness

Within 60 minutes of consuming one packet of Unimate, participants showed a statistically significant improvement in Oxford Happiness Questionnaire scores. Average scores moved from the low 4s to the high 4s, corresponding to a shift from “somewhat happy” to “rather happy.”

Human Study Clinical Trial

The “Feel Great” Program Improves Feelings of Well-Being in Healthy Adults

Following the Feel Great protocol, overall well-being increased 75% after both 30 and 60 days, as measured by the validated SPANE assessment. Positive feelings increased 16% after 30 days and 18% after 60 days, while negative feelings decreased 20% and 18%, respectively.

Human Study Clinical Trial

STRONGHOLD: A Novel Supplement for Muscle Growth and Metabolic Health

Stronghold significantly activated key anabolic signaling pathways involved in muscle growth and repair after a single serving, with elevated anabolic signaling also seen after long-term use. Long-term intake increased muscle mass and muscle-fiber size, reduced fat accumulation and protein breakdown, and improved energy production in muscle. Stronghold also significantly increased GLP-1 both after a single serving and following a short fast with long-term intake, without negatively affecting blood glucose or insulin.

Randomized

The Effect of Soluble Fiber on Glucose Tolerance and Antioxidant Status in Insulin-Resistance Rats

In this 7-week study, subjects fed a high-fat/sucrose diet to induce insulin resistance received either a proprietary soluble fruit-vegetable fiber extract or placebo. The treatment group showed a roughly 27% lower stimulated glucose response than placebo, while plasma retinol increased significantly compared with control. The researchers concluded that the soluble fiber extract may support glucose control and improve antioxidant status in insulin resistance.

Placebo-Controlled

Eight weeks of a novel prebiotic fiber supplement favorably alters human gut microbiota

Over eight weeks, daily prebiotic fiber produced an approximately 4.5-fold increase in Bifidobacterium, a beneficial gut bacterium, while no meaningful change occurred in the placebo group. Lactobacillus also trended upward with supplementation, while Clostridium remained unchanged. Overall, the study found a favorable shift toward beneficial gut bacteria with daily prebiotic fiber supplementation.

Human Study Clinical Trial Placebo-Controlled

The Effects of a Fiber-Rich Nutritional Supplement, Bios Life Slim, on the Glycemic and Insulin Index of Three Common Starchy Foods

Bios Life Slim was consumed with white bread, white rice, and instant mashed potatoes to evaluate its effect on post-meal glucose and insulin responses. The supplement lowered the glycemic index of all three foods from the “high” to “medium” range and also reduced their insulin index. The findings showed that Bios Life Slim dampened glucose and insulin responses to common starchy foods.

Human Study

Feel Great, a dietary supplement and intermittent fasting program, improves glycemic variability in adults

In this CGM study, adults followed their habitual diet for four days and then incorporated the Feel Great program, consisting of Unimate, Balance, and intermittent fasting, for four days. Feel Great significantly reduced glycemic variability from 13.3% to 11.7% — a 12% reduction — compared with baseline.

Human Study Clinical Trial

Yerba Maté (Ilex paraguariensis) Supplement Exerts Beneficial, Tissue-Specific Effects on Mitochondrial Efficiency and Redox Status in Healthy Adult Mice

In this four-week study, Unimate prevented significant weight gain and produced tissue-specific changes in cellular metabolism. Skeletal muscle showed increased ATP production and greater energy-production efficiency, while fat tissue shifted toward greater energy expenditure. Unimate also increased liver glutathione and antioxidant potential, indicating improved protection against oxidative stress. In other words, Unimate helped muscle cells produce energy more efficiently while causing fat cells to use more energy, with more of that energy released as heat.

Randomized Peer-Reviewed Journal

Effect of Unimate on Acute Appetite Suppression Among Adults

In this single-blind exploratory study, healthy adults consumed Unimate after a 12-hour overnight fast and reported appetite responses for 120 minutes. Unimate was associated with lower desire to eat and hunger, greater fullness, and lower prospective food consumption. Among participants who completed both Unimate and placebo conditions, desire to eat was significantly reduced from baseline at 15, 30, and 45 minutes after drinking Unimate.

Human Study Clinical Trial

Viscous soluble fiber combined with phytosterols and policosanol reduces LDL-cholesterol and increases HDL-cholesterol in hypercholesterolemia.

In this 8-week study of 25 adults, BiosLife significantly improved multiple cholesterol markers. LDL cholesterol decreased 4.8% overall, 24.5% among participants starting above 130 mg/dL, and 30.6% among those starting above 160 mg/dL. HDL cholesterol increased 8.3% overall, while total cholesterol decreased 8.2% and the total cholesterol-to-HDL ratio improved significantly.

Human Study Clinical Trial Peer-Reviewed

Bios Life University of Sydney Study 2011

A 2011 report from the University of Sydney’s Glycemic Index Research Service found that when Bios Life was consumed with a white-bread test meal, the post-meal blood-glucose response was reduced by 20% with one serving and 28% with two servings. The blood-insulin response was reduced by 13% with one serving and 27% with two servings.

Human Study

The “Feel Great” program improves cardiometabolic health outcomes in healthy adults

This 60-day study found that the Feel Great program significantly improved multiple cardiometabolic markers, including LDL cholesterol, non-HDL cholesterol, total cholesterol, triglycerides, HbA1c, body weight, and waist circumference. Percent HDL also increased significantly.

Human Study Clinical Trial

A New Fiber Drink Provides a Natural First Line Treatment Option in Mild Hypercholesterolemia

In this six-week study of 41 adults with elevated LDL cholesterol, BiosLife significantly reduced LDL cholesterol, increased HDL cholesterol in participants with low HDL, and improved the cholesterol risk ratio. Among responders with LDL above 130 mg/dL, LDL fell by approximately 20%.

Human Study Clinical Trial

Unimate Acutely Suppresses Appetite and Reduces Caloric Intake in Healthy Adults

This randomized, controlled crossover study found that Unimate increased feelings of fullness by 59% within 15 minutes and reduced caloric intake by approximately 11%, or about 150 calories, at the subsequent meal. The findings support Unimate as a dietary strategy for appetite regulation, caloric control, and weight management.

Human Study Randomized

The Incretin Effect of Yerba Maté (Ilex paraguariensis) Is Partially Dependent on Gut-Mediated Metabolism of Ferulic Acid

This peer-reviewed study found that Unimate increased GLP-1 gene expression and raised circulating active GLP-1 by approximately 45% compared with control. Researchers also identified a gut-mediated pathway in which microbes convert ferulic acid into dihydroferulic acid, a compound that strongly stimulated GLP-1 production in intestinal cells. The findings help explain how Unimate supports the body’s natural GLP-1 response.

Peer-Reviewed Journal

Real-World Improvements in Metabolic Health Following 90 Days on the Feel Great Program

This 90-day observational study found significant improvements among participants following Feel Great—a combination of Balance, Unimate, and intermittent fasting. Average A1c decreased by 0.2 percentage points overall and by 0.4 points among participants beginning in the prediabetic or diabetic range. Of that higher-risk group, 38% moved into a lower-risk A1c category. Participants who provided body measurements also reported reductions in weight and waist circumference, with greater program adherence associated with greater improvements.

Human Study

Fiber-Multivitamin Combination Therapy: A Beneficial Influence on Low-Density Lipoprotein and Homocysteine

This study found that Bios Life 2, also known as Balance, lowered LDL (“bad”) cholesterol and a blood marker called homocysteine in people with high cholesterol. The researchers concluded that regular use could help reduce cardiovascular risk and potentially reduce the need for, or dose of, cholesterol-lowering prescription drugs such as statins.

Human Study Clinical Trial Randomized

Balance Apple Extends Glycemic Benefits Beyond Peak Glucose Reduction

This randomized, controlled crossover study found that Balance Apple improved the glucose response to a high-carbohydrate meal. Compared with the water control, it reduced peak glucose by 20%, reduced the early rise in glucose by 23%, and reduced the post-meal glucose “crash” by 62%, producing a smoother return toward baseline.

Human Study Clinical Trial Randomized

Effect of a Proprietary Matcha Powdered Drink on Thermogenic, Weight, Appetite, Lipid, Blood-Glucose, and Energy Levels

In this 30-day study of 45 adults, twice-daily consumption of a proprietary Unicity matcha drink was associated with significant improvements in body weight, BMI, body-fat percentage, waist and hip circumference, triglycerides, total cholesterol, and LDL cholesterol. Average weight decreased by 1.49 kg, body fat by 2.23 percentage points, waist circumference by 5.4 cm, triglycerides by about 28 mg/dL, and LDL cholesterol by about 13 mg/dL.

Human Study Clinical Trial

Diesel Particulate Matter (DPM)-Induced Metabolic Disruption in Mice Is Mitigated by Sodium Copper Chlorophyllin (SCC)

In a four-week study, Super Green+ supplementation restored lung energy production, reduced oxidative stress in lung and skeletal muscle, lowered key inflammatory markers, and reduced pollution-related enlargement of fat cells.

Randomized Peer-Reviewed Journal